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Nanoscale

Tracking single-molecule ferritin reassembly and disassembly using polymer-coated nanopores

Mahya Assadipapari, Alireza Soleimanian, Max Adam, Jiali Li, Arman Yousefi, Saaman Zargarbashi, Lei Xu, Max F. K. Wills, Hesna Kara, Marina Santana Vega, Alasdair W. Clark, Andrew J. Hudson, Jian‐An Huang, Mohsen Rahmani, Cuifeng Ying

Discovered via OpenAlex

Abstract

, 4-, 6-, 8-, 10-,12-, and 16-mers) during the reassembly and disassembly processes. Through real-time tracking of ferritin reassembly and disassembly dynamics, this approach - combining nanopore coating and individual event analysis - demonstrates potential to characterize single proteins within a mixture, determine their compositions, and track reaction processes in real time.

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